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Chronic oxidative stress, mitochondrial dysfunction, Nrf2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative stress in an animal model of Gulf War illness

Thus, based on our data, we believe that for accurate determination of a new drugs DILI risk, including its placement on the hepatotoxicity spectrum, we absolutely need comprehensive assessment under both acute and chronic treatment conditions

p=0.007), as shown in the inset of Figure 3B

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