nebulized glutathione for lyme disease Smoke Inhalation Glutathione IV Therapy: The Benefits

While significantly lower GSH:GSSG ratios were not seen using traditionally defined severity phenotypes, lower ratios corresponded to a greater history of exacerbations, lower lung function, and higher FeNO

In addition, when GSH is depleted, monocyte-derived macrophages significantly increase their production of reactive oxygen species (ROS), further amplifying oxidative damage within the CNS (Canton et al., 2021)

PMID: 41791543 Int J Biol Macromol S100A4 regulates ferroptosis to suppress cell proliferation via the SLC7A11-GSH axis but facilitates Brucella infection in RAW264.7 macrophages

Alternative repletion strategies have focused on oral administration of GSH precursors (e.g., cysteine and glycine supplementation 9 ), and intravenous administration of GSH, 10 which although promising, is invasive and inconvenient, and therefore unlikely to be a practical solution