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It may also have mild mood-stabilizing effects and is frequently used in formulations targeting metabolic and emotional balance

Figure 2 However, significant heterogeneity in EPA/DHA dosing (0.53 g/d) and ratios across studies, short trial durations (typically 6 months), and a lack of robust structural outcome data (e.g., joint space narrowing) have precluded their formal recommendation as a standard adjunctive treatment in clinical guidelines (44)

Emerging Research and Future Directions 8.1 B12 & Neuroplasticity Ongoing studies are examining B12s role in promoting synaptic plasticity within vestibular pathwayspotentially enhancing long-term adaptation after injury

In addition, a substance which has not been approved for human use is likely to be prohibited as well