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doi: 10.1016/j.redox.2024.103042 50 MarzettiECalvaniRLandiFCoelho-JniorHJPiccaA

Based on findings from the CRND8 mouse model, in which amyloid deposits are associated with neuropathological changes, it is conceivable that similar mechanisms, potentially involving the accumulation of metal ions such as copper, iron, or zinc, could also occur within amyloid plaques in human patients [193, 194]