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BPC-157 works primarily at the injury site for local tissue repair, while TB-500 has more systemic effects on muscle repair, inflammation, and flexibility

Both preclinical and clinical studies show that circadian disruption aggravates BBB injury, characterized by reduced expression of tight junction proteins (ZO-1, occludin, claudin-5), heightened neuroinflammation (TNF-, IL-1), MMP-9/2mediated extracellular matrix degradation, and HPA axis dysregulation

This is a reasonable position, and it is one of the arguments the July panel will need to weigh carefully against the absence of rigorous human trial data

Testosterone Cypionate can be dosed every 3-7 days depending on the initial dose used