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Non invasive CRISPR Cas9 nanocapsules specifically edit synuclein for effective Parkinson's disease treatment ScienceDirect Ferroptosis is a type of cell death driven by uncontrolled peroxidation of membrane phospholipids. Glutathione peroxidase 4 (GPX4) is the main regulator of ferroptosis, but how it protects membranes is not well Genome wide CRISPRi a screens in human neurons link lysosomal failure to ferroptosis bioRxiv Human midbrain organoids: a powerful tool for advanced Parkinson's disease modeling and therapy exploration npj Parkinson's Disease

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