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1 The Components of Each CYANOKIT Each CYANOKIT consists of 1 : Dosing and Administration for CYANOKIT Recommended Dosing for CYANOKIT 1 The starting dose of CYANOKIT for adults is 5 g (contained in a single vial), administered by IV infusion over 15 minutes (approximately 15 mL/min)* Depending upon the severity of the poisoning and the clinical response, a second dose of 5 g may be administered by IV infusion up to a total dose of 10 g The rate of infusion for a potential second dose may range from 15 minutes (for patients in extremis) to 2 hours, as clinically indicated *No safety and efficacy studies have been performed in pediatric patients

The important role of columnar enterocytes in the sampling of soluble antigens is highlighted by studies indicating (i) that antigen transport through afferent lymphatics into the draining mesenteric lymph nodes is obligatory for oral tolerance induction

Age-related influence on thiol, disulfide, and protein-mixed disulfide levels in human plasma

Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L