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It was noted that TFR2 knockdown inhibited TNBC cell proliferation by inducing ferroptosis

Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-kappaB activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Studies have shown that the use of ferrostatin-1 (Fer-1, a ferroptosis inhibitor) can increase T-cell activity, and its combination with anti-PD1/L1 immunotherapy leads to the enrichment of CD8 + T cells in tissues, significantly increasing the immune infiltration of CD8 + T cells ( + T-cell activity ( + T cells and that HFEs can influence their activity in a sex-specific manner

When the organism undergoes oxidative stress, MDA, as a biomarker of lipid and protein oxidation, directly reflects the degree of lipid damage in the body (31)