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Yi Wang received funding from the Sichuan Provincial People's Hospital and a Sichuan Scientific Research Grant for Returned Overseas Chinese Scholars (grant no

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13 , 14 , 16 , 18 , 20 Induction of oxidative stress with glutathione depletion through buthionine- S,R -sulfoximine, oral exposure to H 2 O 2 , or social defeat model through resident-intruder paradigm has been shown to be associated with anxiety and/or depressive behaviors in rodents tested with elevated plus maze, forced swim test and uncontrollable stress models