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Thats a behavioral form of tolerance built through repeated exposure, and its a completely different mechanism from the physiological BAC-dilution effect described in this article

Except for propofol, all the compounds listed in this section are orally active, which could facilitate their potential wider use

Protein translation inhibition through PKR (protein kinase R) or PERK (protein kinase R-like endoplasmic reticulum kinase)-induced phospho-EIF2a (eukaryotic translation initiation factor 2a) is also important for proteostasis and the induction of autophagy 35

Potential Benefits of Using Peptides for Muscle Recovery Some early and preclinical research suggests certain peptides might influence tissue repair pathways, but controlled human trials are limited, so benefits like faster recovery or less soreness have not been demonstrated for many of these agents