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Atawia RT, Toque HA, Meghil MM, Benson TW, Yiew NKH, Cutler CW, et al

These are some examples of how OoC technology can represent a next-generation preclinical testing tool, moving beyond conventional toxicology toward precision immuno-oncology, where patient-derived chips could guide therapeutic decisions and dose optimization while reducing reliance on animal models

Undas A, Williams EB, Butenas S, Orfeo T, and Mann KG (2001)

522 These findings suggest that islet autoantibodies are not pathogenic in type 1 diabetes but rather a consequence of the immune-mediated destruction of -cells