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At 0.5 mg/kg, the highest dose tested, two subjects experienced serious adverse events (SAEs) of stomatitis, a known side-effect of rapamycin 17

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Compared with the low OBS group, the adjusted odds ratio (95% CI) of the high OBS group was 0.17 (0.030.95) for HTN ( The type and number of components comprising the OBS varies across studies