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Mitochondrial dysfunction and neuroinflammation are characteristic of many neurodegenerative diseases such as ALS and HD, thus Nrf2 has become a promising therapeutic target (60)

LF, low frequency

A comparative analysis of multiple sclerosis-relevant anti-inflammatory properties of ethyl pyruvate and dimethyl fumarate

Therefore, KHYG1 NK cells could be considered as an NK cell pool with low CD38 expression that can survive from Daratumumab-mediated NK cell decrease while still capable of mounting a cytotoxic response against MM target cells