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Elimination is considered to be Phase 3 of detoxification

Despite the huge inconsistency of the results, antioxidant enzymes are consistently considered an important player in MASLD development and progression

Gene set enrichment analysis (GSEA) of the transcriptomic data highlighted significant alterations in several key pathways, including ribosome, oxidative phosphorylation, and neurodegenerative diseases such as Parkinsons and Alzheimers (Figures 4D,E)

Given that -helix has 3.6 residues per turn, the most common patterns of inducing covalent cross-links between the side chains of amino acid residues in stapled peptides are separation by approximately one ( i and i + 4 positions), two ( i , i + 7), or three turns ( i , i + 11) of the helix (Figure 3A) [83]