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Description

They play the role of sensors of environmental conditions that dynamically regulate the paracellular transport of solutes (Ulluwishewa et al., 2011)

TRPM7 is a divalent cation channel permeable to Ca 2+ , Mg 2+ , Mn 2+ , and, notably Zn 2+ .[20] Additionally, while carvacrol and 2-APB (TRPM7 inhibitors), reversed neuronal death by reducing Zn 2+ accumulation [21]