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INTRODUCTION Tobacco use was among the five leading risk factors for disability-adjusted life years (DALYs) in 109 countries and territories in 2015, with a rise from 88 regions in 1990 1

10.3390/biom9080334 127 YangQ.HouX.LiuY.ZhangH.FuQ.ZhangF.et al (2019)

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In recent years, an easier pathway to quitting smoking tobacco has appeared in the rise of e-cigarettes and vaping, with many smokers choosing to exchange their old habit for a less dangerous alternative