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Description

A systematic review of the efficacy and tolerability of hydroxyethylrutosides for improvement of the signs and symptoms of chronic venous insufficiency

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Paraxanthine (1,7-dimethylxanthine, PXN) is the main metabolite of CAF, accounting for 7072% of ingested CAF and 85% of the methylxanthine metabolic by-products (Stavric 1988)