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developed a new CaF2 nanocrystal oscillator with a dendritic polymer as a framework to build a nanoplatform with a dual-core satellite structure that is capable of programmatically and spatially separating the dual loading of therapeutic agents, permitting the combination of XPDT and antiangiogenic therapies, thus generating a restorative system capable of synergistically combating tumors [75]

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Costarelli L, Muti E, Malavolta M, Cipriano C, Giacconi R, Tesei S, et al

Studies using cardiac-specific Atg5 deletion models have been pivotal in establishing this concept (Fig