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We note that, if calculated without applying our proposed methodology for incorporating an estimate of outlier reconciliation in the determination of the outlier threshold, the proposed threshold would be $40,808

Thiostrepton (TST, purity ~99%), RSL3 (purity ~99%), and ferrostatin-1 (Fer-1, purity ~99%) were purchased from MedChemExpress (MCE, USA) and dissolved in dimethyl sulfoxide (DMSO)

Consistent with this, our RNAseq analysis revealed significant alterations in the expression of genes involved in glutathione metabolism following melatonin treatment ( Figure 6A )