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RCC with high lysosomal protein transmembrane 5 (LAPTM5) expression maintains the self-renewal of stem cell-like characteristics by blocking the organ-specific inhibitory signals from BMPs [241]

Science 343 , 189193 (2014)

For example, in USP38-TG diabetic mice, pharmacological inhibition of RAGE with FPS-ZM1 attenuated cardiac systolic and diastolic dysfunction by improving LVEF, LVFS, and E/A ratio, reduced myocardial fibrosis, enhanced cardiac electrical stability, and suppressed inflammatory marker expression [166]

In magnetosomes, the radicals are likely retained on the surface of the Fe 3 O 4 core or confined by the lipid membrane, preventing their diffusion and contributing to an antioxidant effect by decomposing H 2 O 2