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This work was possible thank to the financial help of Fundacin de Investigacin HM Hospitales and Tecnologico de Monterrey

Results announced in October 2025 demonstrated orforglipron's superiority on both HbA1c and weight endpoints, positioning it as a more effective second-line oral agent than existing oral diabetes medications

And while the studies measured total body weight rather than visceral fat specifically, imaging substudies have shown that GLP-1 agonists reduce both visceral and subcutaneous fat compartments

It plays a central role in cellular detoxification, the neutralisation of reactive oxygen species, and the regeneration of other antioxidants including Vitamins C and E