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For example, the optimal pH for the CD39 enzyme is in the alkaline range of 88.3 ( Also, the fact that CD203a has a lower affinity for its substrate ATP than CD39 supports the idea that the alternative ectoenzymatic CD38/CD203a tandem using NAD + as substrate (Figure 1) may become a relevant producer of AMP for ADO production in the BM niche

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If you would like clinician follow-up without returning for an in-person visit, Tonums research and telehealth resources can be a helpful next step