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10.3389/fmicb.2017.02677 161 SinghR

I was given prednisone for tendonitis in my glutes after a chiropractor worked on my sciatica and he pulled one of my tendons in my leg too hard

In earlier work, Sekhars group had shown that in healthy adults, the levels of oxidative stress, oxidative damage and glutathione remain stable until people enter their 60s, when oxidative stress and oxidative damage begin to increase and glutathione to decline

This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation