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Heat shock transcription factor 1 (HSF1) is a master regulator of proteostasis 30,31,32 which was recently reported to promote proteostasis and the regenerative activity of HSCs in response to culture stress and aging 33

In the BV2 cells (a mouse microglial cell line), Cu could trigger activation of the NF-B signaling pathway and increase the release of inflammatory factors such as nitric oxide (NO) and the cytokine tumor necrosis factor- (TNF-)

In line with our previous results [36], cells subjected to a 96 h incubation with Palbociclib displayed enhanced rates of glucose and glutamine consumption and of lactate and glutamate production (Fig

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