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To directly establish that E2F1 stimulates the expression of ATAD2 in melanoma, we knocked down the E2F1 expression using shRNA and measured ATAD2 expression

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Rebouche CJ, Engel AG: Carnitine metabolism and deficiency syndromes

In addition to targeting specific enzymes, drugs aim to improve efficacy and reduce adverse reactions by focusing on specific distribution and functions in the pathological stage