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Karantas, Neslihan stnda Okur Applied Sciences.2025

Importantly, Gclc -deficient FoB accumulate ROS (Fig

These Fe-S clusters are essential cofactors for several critical enzymes involved in the TCA cycle and ETC complexes I-III (8)

In summary, the cyclic warhead scaffold provides a structural platform to fine-tune JNK inhibitor reactivity and selectivity by using different substitution patterns in rationally selected ring positions