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Scientific References Hydroxocobalamin 1mg/ml Solution for Injection SmPC (emc)

Studies show that NNMT inhibition by 5-amino-1-methylquinolinium significantly reduces nicotinamide metabolism, increases NAM accumulation, improves NAD+ synthesis efficiency by over 30%, and markedly increases mitochondrial ATP production and cellular energy metabolism

ANCOVA analysis was performed and revealed similar results to the previously mentioned findings when controlled for IFG/diabetes conditions at the time of screening