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Since NAD therapy has not been approved by the FDA to help manage opioid addiction, it should only be used as part of an existing recovery program that includes evidence-based treatments such as: Behavioral therapy , in which a mental health professional helps you change unhealthy thoughts and behaviors related to your addiction Medication-assisted treatment (MAT) , in which you are prescribed medications like buprenorphine, methadone, or naltrexone to ease opioid cravings and withdrawal symptoms When used alongside these treatments, BR+ NAD therapy may help support cellular recovery during withdrawal, making early recovery feel more manageable

In contrast, TA administration alone did not result in a significant increase in MDA levels