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doi: 10.3389/fphys.2024.1326392 41

Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity

Data processing Tumor size was measured as the sum of manually contoured tumor areas in each slice multiplied by slice thickness using in-house software 49

Compared to a similarly unoptimized ENL PROTAC designed with a traditional CRBN ligand, dHTC1 afforded several other improvements, including improved selectivity, more durable degradation over time, and better pharmacokinetic properties