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These findings consistently emphasize the importance of changes in the concentrations of various ions in the extracellular environment of neurons, and it is possible that targeting the concentrations of ions in the environment to permanently regulate the splicing of neurexins and thereby interfere with synaptic plasticity could be one of the mechanisms of sustained antidepressant effect

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By combining these two peptides in controlled research settings, scientists can investigate how dual receptor activation influences endocrine signaling