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Importantly, this work also revealed the synaptic and behavioral abnormalities in these models of ASD [172, 173, 175] that were reversed by the selective nNOS inhibitor 7-nitroindasole [172, 173]

By pretreating with a nanoprimer before LNPs loaded with RNA therapeutics, the bioavailability of RNA-loaded LNPs significantly improved (Saunders et al., 2020)