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The broad-spectrum inhibitor -CHCA reduces lactate export and sensitizes tumor cells to chemotherapeutic agents in preclinical models 159,160

65 , e2100536 (2021)

Collectively, this study identifies GGCT as a metabolic switch that diverts Gln flux toward GSH synthesis to maintain redox homeostasis, while enhancing glucose-fueled anaplerosis into the TCA cycle to sustain cell proliferation

L-carnitine (L-C) is a non-essential dietary amino acid synthesized from lysine and methionine, involved in adenosine triphosphate and energy generation [3,4,5]