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This formula has a history of over 2,000 years in China and is widely employed to treat various types of depression due to its liver-soothing, depression-relieving, spleen-nourishing, and blood-nourishing effects (Li et al., 2022)

Melatonin inhibits the ferroptosis pathway in rat bone marrow mesenchymal stem cells by activating the PI3K/AKT/mTOR signaling axis to attenuate steroid-induced osteoporosis

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Notably, Ataluren forms hydrogen bonds with His 153 and Arg 174 , a salt bridge with Arg 174 , and a -stacking interaction with Phe 113