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199 Even with various antioxidant systems in place, the production of ROS could surpass the ability of the defense network, leading to oxidative stress

People who regularly drink heavily can also have changes in metabolism some develop tolerance, but heavy chronic drinking can impair the livers efficiency over time

Because of the side effects in people, however, it was relegated for use in veterinary medicine

Additionally, four peptides constituting KLOW have not been studied altogether in human clinical trials, therefore the side effects caused by this peptide is not well-documented and hence, research on the individual peptides and anecdotal reports from users are relied upon to know their respective side effects