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These adjuvants were chosen for their clinical relevance and proven ability to elicit broad immune responses, including diverse effector T cell subsets and functional antibodies across multiple species ( , an adjuvant used in licensed influenza vaccines ( 2 Results 2.1 Identification and selection of mycobacterial antigens Building on the work of Bettencourt et al

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doi: 10.1056/NEJMcp1113996

Three specific gaps separate this preclinical evidence from a human recommendation, and it is worth naming each so the framing throughout this guide is not mistaken for false modesty