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3.2 Non-pharmacological treatments of PDs The non-pharmacological treatments of PDs include various approaches like physical, occupational, speech, and nutritional therapy and exercise (58, 59)

Researchers continue to investigate these mechanisms, and additional work is needed to better understand how they function in different experimental models

In nude mice-transplanted tumors, PUMA plays a critical role in the taurine action against lung cancer and may signify a novel target for gene therapy in lung cancer [45].Taurine prevented nitric oxide-induced apoptotic cell death in murine RAW264.7 macrophages [46] and myocardial ischemia-induced apoptosis by preventing the assembly of the Apaf-1/caspase-9 apoptosome [47]