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Their findings revealed a significant reduction in glucose production and expression of both G6pc and Pck1 in hepatocytes with NNMT overexpression and concurrent Sirt1 inhibition, compared to hepatocytes with NNMT overexpression alone

Front Cell Dev Biol 2021;9:695015.ArticlePubMedPMC 178

Public Health 136 , 123124 (2016)

Among the genes most substantially upregulated by BPC157 exposure was the growth hormone receptor (GHR), identified as one of the most abundantly induced transcripts across the experimental gene expression dataset