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doi: 10.1111/jgh.12019 53

Given that the PI3K/AKT signaling pathway is one of the most important oncogenic cascades in human cancers 36 , and its activation has been shown to enhance aerobic glycolysis and accelerate OS progression 19 , we examined whether MAT2A influences this pathway

In addition to improving insulin sensitivity, metformin also appears to promote healthy fat distribution, which is typically deregulated in HAART-treated HIV patients