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Intensive Care Med (2016) 42(5):699711

LaccIDs inactivity in the ER may result from limited intracellular copper, which is supplied by copper chaperones localized predominantly in the Golgi 34

If you disbelieve the studies (which the failed replications support), then the dose question is moot

since chronic perifollicular micro-inflammation and oxidative stress are thought to contribute to follicle decline, these actions are theoretically supportive