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Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

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Immunofluorescence analysis of SREBP2 expression in Huh-7 cells showed that compared with the CON group, the ALC group had significantly reduced SREBP2 levels, and similarly, compared with the TG group, the ALC + TG group had significantly reduced SREBP2 levels (Figures 6F,G)