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SUMMARY Cisplatin is a platinum-based coordinate compound that is actively used as first-line therapy for the treatment of various solid tumors and cancers because of its anticancer activity

Necrotic tubular cells release damage-associated molecular patterns (DAMPs) and trigger secretion of pro-inflammatory cytokines and chemokines in tissue-resident cells and recruited leukocytes [111]

Results JA, OPDA and GSH are involved in regulation of gene expression during recovery from HL treatment Global gene expression analysis was performed after the HL treatments of 15 and 60 min (HL15 and HL60) and after subsequent R phases in GL for 15 (R15) and 60 min (R60), and the results were expressed with respect to GL control without any HL treatment

[15] Animal model studies with GGC have supported a potential therapeutic role for GGC in both the reduction of oxidative stress induced damage in tissues, including the brain [16] and as a treatment for sepsis