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& Baatz, J

Rana et al., 2020)

Rapid and accurate predictions of perfect and defective material properties in atomistic simulation using the power of 3D CNN-based trained artificial neural networks

In vitro COMT inhibition assays demonstrated that the tolcapone-loaded PLGA nanoparticles achieved comparable enzyme inhibition efficacy to free tolcapone, confirming therapeutic retention which was achieved in addition to a controlled-release profile and reduced cytotoxicity