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When patients ask about GHK-Cu peptide benefits, they are usually referring to a cluster of clinically observed effects: better firmness, smoother texture, more even tone, and improved tolerance for procedures

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The downstream signaling target of PI3K/AKT is mTOR, which is a serine/threonine kinase, also called the mammalian target of rapamycin [108]

Abbreviations AGEs: Advanced glycation end products CP: Citrus pectin ECM: Extracellular matrix FRAP: Ferric reducing ability of plasma FTIR: Fourier transform infrared spectroscopy GPx: Glutathione peroxidase HG: Hemogalacturonan HM: High methoxyl pectin HMGB1: High mobility group box 1 LM: Low Methoxyl pectin NIDDM: Non-insulin dependent diabetes mellitus NPs: Nanoparticles PKC: Protein kinase C RAGE: Receptor for advanced glycation end products RAPID: Risk Assessment of Pakistani People for Diabetes RG-I: Rhamno-galacturonan-I RG-II: Rhamno-galacturonan-II ROS: Reactive oxygen species SCFAs: Short chain fatty acids SOD: Superoxide dismutase VEGF: Vascular endothelial growth factor References Noreen A, Akram J, Rasul I, Mansha A, Yaqoob N, Iqbal R, Tabasum S, Zuber M, Zia KM