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A spiroquinolamide derivative, listatproxin1, was reported to be effective in inhibiting ferroptosis [28]

Hereditary folate malabsorption Cerebral folate deficiency ( CFD ) Neural tube defects ( NTDs ) Kearns-Sayre syndrome Autism spectrum disorders ( ASDs ) (1) Hereditary folate malabsorption Folate deficiency in the CNS, denoted by low-levels of cerebrospinal fluid ( CSF ) 5-methyl-THF concentrations, has been implicated in disorders involving defects in folate transport systems

Policastro L, Molinari B, Larcher F, Blanco P, Podhajcer OL, Costa CS, et al

Furthermore, their integration with immunotherapy strategies can establish a multimodal synergistic therapeutic framework