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Description

Since DFO is membrane impermeable and accumulates in lysosomes 18 , we believe that it protects the cells against ferroptosis by chelating lysosomal iron as described previously 47

Berthet P

doi: 10.1074/jbc.274.5.3009 55 SatoHTambaMIshiiTBannaiS

The fact that most of the studies included only live-born infants and did not record or observe stillbirths, spontaneous abortions, or induced abortions due to severe malformations, potentially led to underestimations of the strength of the associations between SSRIs and fetal congenital malformations