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Genistein protects epilepsy-induced brain injury through regulating the JAK2/STAT3 and Keap1/Nrf2 signaling pathways in the developing rats

aeruginosa , and E

N Engl J Med 383:989992

This initiates the extrinsic pathway and further amplifies mitochondrial damage through BH3 interacting domain death agonist (BID) cleavage, linking both pathways at the mitochondrial level (Stergiou and Hengartner 2004)