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We attempt to characterize quality and gross defects in condition whenever possible as an aid to prospective bidders, but clients should satisfy themselves prior to the sale as to the condition of each lot and should exercise and rely on their own judgment as to whether the lot accords with its description

Due to the high mutation rate of malignant cells with defects in the p53 pathway and the fact that mutant p53 proteins are only highly expressed in malignant tissues but absent in normal tissues, targeting mutant p53 itself has been proposed to be a promising strategy for improving the treatment of chemo- and/or radio-resistant tumours

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