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When subjected to the inflammatory cytokines IL-1 or TNF-, the upper layer of chondrocytes also notably promoted the differentiation and fusion of the underlying osteoclasts

Carson, University of Tennessee Health Science Center (UTHSC), United States Reviewed by Tsutomu Matsubara, Osaka City University, Japan Jordi Muntan, Institute of Biomedicine of Seville (CSIC), Spain Updates Copyright 2022 Zhou, Zheng and Chen

Its activation has been reported across various pain states, including acute, chronic, and neuropathic pain (21, 29)

Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health