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People often assume a sprain will heal on its own, returning to activity before tissues have properly remodeled

Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, et al

The presence of FAD-binding region and transmembrane hemes enable NOXs to act as an electron-transportation chain that transfers two electrons from cytosolic NADPH to extracellular O 2 , resulting in the generation of O 2