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Its activation can be triggered by fatty acid derivatives, lycopene-rich wolfberry pigment, and tea seed saponins, either directly or indirectly via AMPK and SIRT1 signaling (183)

P Perez-Pardo T Kliest HB Dodiya LM Broersen J Garssen A Keshavarzian AD Kraneveld 2017 The gut-brain axis in Parkinsons disease: possibilities for food-based therapies Eur J Pharmacol 817 86 95 K NV, S M (2025) Aging through the lens of the gut microbiome: Challenges and therapeutic opportunities

Statistical analyses All studies were conducted three times, with the exception of the mass spectrometry studies which were conducted twice

Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis